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History

What Is Platelet-Rich Plasma

Platelets are blood cells made in the bone marrow. They are made up of protein packs that are responsible both for wound healing and clotting. After platelets are released from the marrow into the bloodstream, their circulating lifespan is approximately 7-10 days. Platelets can accumulate at the site of acute injury.

The formation of a blood clot, followed by the release of growth factors, is a sequence of events. These growth factors draw other blood cells to the region. These growth factors and other cells aid in healing. To stimulate growth factors' release, many people have used calcium chloride and human thrombin (Recothromb).

Bovine thrombin can also be used but there have been some reports of hypersensitivity reactions among a few patients. A concentrate of whole blood that has at least 1,000,000 platelets per 6 cms is called platelet-rich plasma (PRP). Platelet concentrations between 3-5 million and 5-6 million are ideal, as higher platelet counts can lead to faster healing and more growth factors.  To get a PRP preparation kit for treatment, you can hop over to this site 5linebiologics.com/platelet-rich-plasma.

Where has PRP been used?

Some authors presented a non-randomized study on 20 patients suffering from chronic lateral epicondylitis (tennis knee) and presented the results. Eight weeks later, the patients were evaluated and found that there was a 60% improvement in PRP treatment compared to the 16% in the control group.

This treatment was also used to treat Achilles tendon issues. These results were mixed. In a Dutch study, 54 patients were compared in a 2010 Journal of the American Medical Association. There was no statistical difference in the PRP-treated group versus the exercise and saline groups.