Psychedelics are powerful substances that alter perception, mood and cognition. Psychedelic uses have been a part of human history for thousands of years – for both spiritual practice and recreation – and they have been the focus of intense debate.
Psilocybin is a serotonin receptor agonist that targets the same route as existing antidepressants, albeit via a different mechanism. You can also purchase magic mushrooms online via mungus.
Psilocybin changes emotional bonds from negative to positive stimuli, in part by reducing amygdala activity. Several studies have looked at the use of the compound in cancer-related stress, late-life anxiety, obsessive-compulsive disorder, and smoking and alcohol addiction.
Proponents of this new study state the safety and effectiveness of psilocybin and encourage future research with more stringent designs. People who oppose the use of psychedelics for medicinal purposes cite the belief that psychedelics negatively impact mental health.
However, there is no evidence to confirm this, and few studies have actually shown a reduction in psychological stress and suicidal thoughts compared to other drug users. Psychedelics, especially psilocybin, also have a low risk of addiction or compulsive use. Psychedelics are generally considered physiologically harmless.
Depression affects nearly 7% of American adolescents and adults. Despite the large number of drugs used to treat depression and the long-term success of cognitive behavioral therapy, 20% of patients do not respond to treatment and many have relapses.
New and long-term therapies are needed for depression, and psychedelics can be the door (or mirror) that researchers must go through to find effective drugs.